The nationally recognized, not-for-profit Hospital is home to four Centers of Excellence: The Robert and Beverly Lewis Family Cancer Care Center, Stead Heart and Vascular Center, Women's & Children's Center, and Trauma Center, and offers a full-service Emergency Department, Neonatal Intensive Care Unit and Perinatal Center. Specialized services include sleep disorder diagnosis and treatment, robotic surgery, and the Family Medicine Residency Program, in affiliation with the University of California, Los Angeles.

The new Robert and Beverly Lewis Outpatient Pavilion houses an outpatient surgery center and rehabilitation services center. The outpatient surgery center has five outpatient surgical suites with state-of-the-art technology. The Charles M. Magistro Physical Therapy and Rehabilitation Center has the latest evaluation and exercise equipment, including telemetry treadmills and neurological suspension devices, as well as diagnostic programs and integrated technologies and software systems.

PVHMC also provides a wide range of other outpatient services such as urgent care, radiology, including 3D mammography, and occupational health to the surrounding cities of Pomona, Chino, Chino Hills, Claremont, Eastvale, Corona, Diamond Bar, Walnut, Ontario, Riverside, San Bernardino La Verne and eastern Los Angeles counties.